URDMC has strong operational presence in Acholi and West Nile region in Northern Uganda since 2012. In 2024,URDMC explore expansion to Mid North and South Western Uganda delivering both humanitarian and developmentinterventions. The current districts of operation are; Lamwo, Adjumani, Yumbe, Terego, Madi Okollo, Koboko, Kiryandongoand Kyegegwa with Arua City as the Head Office.
The targeted refugee settlements, reception centres, transit centres andcollection points include; Palabek, Lokung, Nyumanzi, Goboro, Kerwa, Kuluba, Imvepi, Omugo Rhino Camp extension,Ocea, Kiryandongo and Kyaka II.